Expanded Primary Hepatocytes: Achieve More Predictive Toxicity Studies

Choosing the ideal model for toxicological research and screening poses a challenge to the researcher. On one hand, you want the high biological relevance of a primary cell so you can trust that your assay is predictive of the in vivo situation. On the other, you need the proliferative capacity of a cell line to provide a copious quantity of cells so you can test all of your variable conditions. ATCC upcyte® Hepatocytes provide both qualities. This advanced hepatic model exploits a growth method that directs non-dividing primary cells to proliferate without altering their biological properties, allowing for the generation of large batches of homogeneous yet physiologically relevant hepatocytes. This webinar will provide an overview of upcyte® Hepatocytes, highlighting the various uses for the cells, such as hepatoxicity prediction and drug-drug interaction studies.



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